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World-class instrumentation for life scientists

CANCER RESEARCH TOOLS – Colony Counter, Hypoxia Workstation, Dissolved Oxygen Monitors, Laser Doppler Blood Flow Monitors

Automated counting of mammalian-cell colonies, spheroids and organoids

GelCount is the leading colony, spheroid and organoid counter for cancer biologists.

  • A dedicated colony counter for processing tumour colony forming cell assays
  • All-in-one solution for imaging, counting and characterizing colonies, spheroids and organoids
  • Substantial throughput advantages compared to manual microscope counting
  • Objective, unbiased colony/spheroid detection
  • Direct export of colony counts, diameters and more to Excel
  • Offline image processing support for maximum throughput and user convenience

AUSTRALIAN RESEARCH STORY – How to kill more cancer cells without increasing the dose of radiation
LRogers-Gelcount-team 

Sydney research team at Chris O’Brien Lifehouse Comprehensive Cancer Hospital

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GelCount

COMPACT HYPOXY CHAMBER TRANSFORMING TISSUE CULTURE RESEARCH

The unique HypoxyLab™ by Oxford Optonix is a new generation workstation and incubator that enables precisely controlled levels of oxygen, carbon dioxide, temperature and humidity within a highly stabilized HEPA-filtered clean environment.

Providing precise, reproducible and physiologically relevant cell environments, the system provides conditions and data that are increasingly considered as vital for an accurate analysis of cellular processes with respect to function and metabolism. The fast growing user base includes cancer, stem cell, human virology researchers as well as multidisciplinary teams in drug development and proteomics.

Highest level of accuracy

  • Better reproducibility. Regulated using oxygen partial pressure for true hypoxia, HypoxyLab enables researchers to provide cells with consistent amounts (and percentages) of oxygen in any location at any time, irrespective of altitude or barometric pressure.
  • Physiologically relevant Mimics the in vivo oxygen environment of cells.

Efficient and easy to use

  • Fully featured with touch-screen controls. Complete, easy control including O2, CO2, temperature, and humidity. Real-time data is displayed in both digital and graphical format with easy transfer to other devices for further analysis.
  • Fast set up. Rapid equilibration in a matter of minutes allows easy sharing between groups.
  • Easy entry for quick transfer. Ergonomic design includes simple front entry hatch as an easier alternative to air lock systems for quick, convenient transfer of cells, culture-ware and media.

Compact and portable

  • Compact, benchtop design. Suits labs with limited space or portable use on trolley.
  • Spacious interior. 48% larger in 2021 release compared to the previous model.

Low cost of ownership

  • Frugal gas consumption. Provides significant cost savings.
  • Service free sensors, user changeable HEPA filter.

Diverse research opportunities using multiple powered devices

  • Seamless integration of powered devices including digital microscopes, shakers, or micro-centrifuges using the system’s cable-through ports.

Time-saving cleaning

  • HEPA filtration is standard. Fast air cycle through filter at startup is less than 30 seconds.
  • Ultrasound nebulizer for internal humidification. No need to add pan of water and potential source of contamination.
  • Simple cleaning protocols. Includes easy removal of cover.

Easy add-on solutions

  • OxyLite™  in situ dissolved oxygen measurements. OxyLite measures oxygen level in the media. These can be different from the atmospheric conditions as diffusion between air and media takes some time.
  • CytoSMART Lux2 microscope for imaging cells without removal. Provides real time imaging and analysis. Enables tracking of kinetic cell activity such as confluence or scratch assays.

Contact us to learn more

“The HypoxyLab has been a great addition to our laboratory. It’s very easy to use, making it straightforward to achieve accurate and consistent levels of hypoxia. It has a small footprint and uses less gas than most other workstations.”

Dr Dan Peet

Associate Professor at the School of Biological Sciences, The University of Adelaide

Tissue vitality monitoring

OxyLite oxygen monitors measure tissue oxygen tension (ptiO2) directly, making them valuable to life scientists studying oxygen supply (by the blood) and consumption (by the tissue) in vivo and in vitro.

OxyLite™ Pro systems provide what is simply the most advanced, accurate and reliable tissue oxygen monitoring platform on the market.

A key feature of OxyLite systems is their ease of use:

  • Fully ‘plug and play’; no calibration procedures, no sensor drift making them the world’s easiest-to-use dissolved oxygen monitors
  • Single, 2 or 4-channel monitors

Applications include cancer biology, stroke and brain injury, transplantation and shock monitoring, spinal cord injury, tissue flap and wound oxygenation, and in vitro dissolved oxygen measurement.

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    Laser Doppler Tissue Flow Monitor

    The OxyFlo series of Laser Doppler tissue flow monitors provide continuous, real-time tissue perfusion assessment. A range of probe types and probe formats provide support for both invasive or non-invasive tissue blood flow assessment.

    Applications typically monitor the competence of microvascular blood supply in specialties such as peripheral vascular disorders, cerebral perfusion in models of stroke and brain injury, tumour perfusion, angiogenesis, blood flow in free flaps and pedicle flaps, wound healing, surgery, transplantation and more.

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    Combined Systems

    Combined systems – OxyLite and OxyFlo are stacked systems enabling the measurement of tissue oxygen, laser-Doppler blood flow and temperature simultaneously from the same tissue micro-region.

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    OxyLite and OxyPro
    OxyLite_OxyFlo_Oxford_Optronix

    Bedside bleed-air 02 monitor for mechanical CPAP devices (COVID-19 SOLUTION)

    Flo-Ox™ is a portable, pole-mountable, bedside oxygen monitor oxygen concentration monitor for mechanical CPAP devices. The monitor was developed in response to an emergency COVID-19 call by the UK’s National Health Service (NHS) and features:

    • Continuous display of % oxygen
    • Min/Max alarm function
    • Touch-screen display
    • Fully factory pre-calibrated
    • No set up required

    Flo-Ox™ was awarded a temporary waiver by the UK MHRA for patient use for the treatment of COVID-19. Full CE marking to be sought in the near future.

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    Oxford Optronix Flo-Ox