Advanced PV Loop Solutions for Clinical and Preclinical Cardiology

PV Loop Systems – clinical and preclinical range

CD Leycom’s comprehensive suite of pressure–volume (PV) loop systems cater to both human clinical practice and preclinical cardiovascular research. The systems, sharing common architecture, deliver simultaneous pressure and volume measurement with high fidelity – offering a real-time, beat-by-beat view of ventricular performance.

Unmatched Depth of Analysis

PV loops are widely regarded as the gold standard for evaluating cardiac mechanics. Continuous, high-fidelity data enable assessment of contractility, compliance, preload, afterload, and overall efficiency—offering physiological depth that single-parameter methods cannot match.

Preclinical Systems for Animal Models

Bi-V Sigma-M PV Loop System

Engineered for preclinical research for small and large animals, the preclinical PV Loop system provides simultaneous left- and right-ventricular monitoring, revealing chamber interactions and hemodynamic relationships that cannot be observed with single-ventricle systems.

Typical Cardiovascular Applications

• Pulmonary hypertension research
• Biventricular physiology studies
• Disease modelling
• Therapeutic evaluation and mechanistic investigations

Key Performance Features

• Reusable high-resolution, high-fidelity conductance catheters providing reproducible pressure and volume measurements across diverse animal models

• Stable performance suitable for longitudinal studies, interventional protocols, and translational research

• Fully integrated hardware and Conduct NT™ software for streamlined acquisition and analysis

• Modular system architecture that adapts to evolving preclinical research needs

• Reusable, cost-effective catheters designed specifically for preclinical workflows

Clinical Systems For Human Use

Inca PV Loop System

The Inca system provides real-time hemodynamic data during diagnostic catheterisation and interventional procedures.

Advanced cardiac assessment applications

• CRT optimisation
• Structural heart and valve interventions
• Congenital heart disease
• Heart failure evaluation
• Right-heart assessment, including pulmonary hypertension

During surgery or catheter-based procedures, continuous PV feedback helps clinicians verify procedural success, guide therapy adjustments, and observe immediate physiological responses.

Human-Use PV Loop Catheters

The clinical conductance catheters enable simultaneous, calibrated pressure and volume measurement via a single catheterisation. Their precision and biocompatibility support reliable performance in demanding clinical environments.

Key Performance Features

• Beat-to-beat real-time PV loop acquisition for immediate procedural decision-making

• Simultaneous pressure and volume measurement with high fidelity

• Single-catheter approach reducing procedural complexity

• Stable signal quality suitable for prolonged and complex interventions

• Calibrated volume measurement using conductance technology validated in clinical workflows

• Compatible with a wide range of catheterisation labs and interventional settings

• Robust performance in dynamic physiologic states, including rapid pacing, ventricular unloading, and acute hemodynamic shifts.